4/13/2023 0 Comments Over secretion of adrenal glandImaging is then obtained, if not already performed, and in most cases adrenal vein sampling (an interventional radiology procedure) is performed. Diagnosis is inferred from laboratory work. This constellation of findings is now known as Conn's syndrome.ĭiagnosis of primary hyperaldosteronism is confirmed by having an elevated aldosterone level and decreased renin level with an aldosterone:renin ratio of at least 20:1. Conn was the first to identify findings associated with excess aldosterone production. Jerome Conn as director of the University of Michigan Metabolism Research Unit in 1943. University of Michigan's preeminence in the field dates back seven decades to the appointment of Dr. When excess aldosterone is produced by the adrenal glands or an adrenal nodule, patients often present to their physician with new elevation of blood pressure (hypertension) and low potassium (about 40% of patients). Aldosterone normally helps regulate fluid status in the body, sodium and potassium levels, and affects blood pressure. Aldosteronoma/Primary Hyperaldosteronism (Conn's Syndrome)Īn aldosteronoma is an adrenal tumor which makes excess amounts of aldosterone.
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